The newest omicron COVID-19 booster shots from Moderna and Pfizer-BioNTech do not increase neutralizing antibodies, proteins produced in the body that help prevent infection, against omicron subvariants BA.4 and BA.5 compared to four of the original COVID-19 shots, according to a small-scale independent study.
The study suggests that the omicron booster may not protect people from getting infected with the highly transmissible subvariant BA.5, which accounts for most COVID-19 cases in the U.S. currently, any more than the previous shots, despite the updated boosters being formulated to provide better protection against infection and severe disease against the current strains.
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